High-Accuracy Automated 360-Degree Dispensing Valve for Microplate Fillers and Liquid Handling Robots with Low Dead Volume

High-Accuracy Automated 360-Degree Dispensing Valve for Microplate Fillers and Liquid Handling Robots with Low Dead Volume

Product Description:

Drive innovation in life sciences with our high-accuracy 360-Degree Dispensing Valve, engineered for integration into automated liquid handling systems and microplate filling stations. This valve is critical for applications requiring high precision and reproducibility, such as PCR setup, next-generation sequencing library preparation, and assay reagent dispensing. Its key feature is an exceptionally low dead volume, minimizing costly reagent waste and preventing cross-contamination between samples. The valve's omni-directional capability is not just for manual use; it allows robotic systems to approach microplates and vial arrays from the most efficient robotic path, reducing cycle times and increasing throughput. Built from biocompatible and PCR-inhibitor-free materials, this liquid dispenser ensures the integrity of sensitive biological samples. The rapid-response solenoid-actuated one-way valve delivers precise, nanoliter-scale droplets with exceptional consistency, making it a foundational component for scalable and reliable lab automation.

Bullet Points:

• Ultra-low dead volume design minimizes reagent waste and prevents sample carryover.

• Enables high-speed, high-precision dispensing in automated robotic liquid handling systems.

• Constructed from biocompatible, non-cytotoxic materials that are certified PCR-inhibitor free.

• Omni-directional integration allows for optimized robotic arm movement paths.

• Provides highly consistent droplet formation for nanoliter to microliter volumes.

Specific Application Scenario
In a high-throughput genomics lab, a liquid handling robot is dispensing master mix into a 384-well microplate for a qPCR reaction. The robot arm, equipped with this valve, moves swiftly between wells, dispensing identical 2-microliter droplets into each well from a consistent height and angle, ensuring uniform reaction conditions across the entire plate with no cross-contamination.

Factory Production Floor
Production for biotech valves occurs in an ultra-clean environment to prevent particulate contamination. The manufacturing of the low-dead-volume flow path requires micron-level precision machining. Each valve is flushed with purified water and tested for volume accuracy using gravimetric methods. A certificate of analysis is provided with each batch, detailing biocompatibility and performance validation.

Packing and Transportation
Valves are packed in a class 100 cleanroom environment. They are triple-bagged: an inner sterile bag, a middle bag sealed in a cleanroom, and an outer protective bag. They are shipped in temperature-stable containers with humidity indicators to ensure they arrive in a pristine state, ready for integration into sensitive laboratory equipment.

FAQ

1. What is the typical dead volume of this dispensing valve?

   • The dead volume is typically less than 5 microliters, which can be further minimized based on the tubing and fitting setup, making it ideal for precious and expensive reagents.

2. How does the omni-directional feature integrate with a specific liquid handling robot?

   • The valve provides a consistent fluidic interface regardless of orientation. This allows system integrators to mount the valve in the most ergonomic position for the robot's range of motion, simplifying the fluidics design and improving maintenance access.

3. Can this liquid dispenser handle viscous biological samples like glycerol stocks or genomic DNA?

   • Yes, it is designed to handle a range of viscosities. For highly viscous samples, we can specify a valve with a larger internal diameter and a more powerful actuation system to maintain dispensing accuracy.

4. Is the one-way valve compatible with continuous flow applications, or is it strictly for droplet dispensing?

   • While optimized for repetitive, discrete dispensing, it can be used in low-pressure continuous flow applications. The response time and seal design make it best suited for start-stop dispensing cycles.

5. What documentation is provided to support our ISO 13485 / GMP compliance?

   • We provide a full Device History Record (DHR) including material certifications, manufacturing process validation reports, and full traceability for all components, supporting your regulatory submissions for diagnostic and therapeutic products.